Mass spec lab

The UNC Department of Chemistry Mass Spectrometry Core Laboratory (MSCL) specializes in small molecule analysis. Our services include, but are not limited to: small molecule quantitation using chromatography (gas or liquid) coupled to mass spectrometry (MS). We also support high-throughput catalysis research for inorganic and organic research ...

Aug 23, 2023 · Mass spectrometry (MS) is a valuable tool that can give you vast amounts of MS data to help you identify and quantify components. MS has been used to discover, determine, and quantify sample compounds in the proteomics, metabolomics, imaging, and glycomics applications across the food, pharmaceutical, and environmental industries. Combining MS with appropriate software and computer technology ... Mass Spectrometry Laboratory Since 1965, the Mass Spectrometry Facility (MSF) has provided top-quality mass spectrometry support to the faculty research groups of the Indiana University-Bloomington. The MSF is one of many technical support facilities in the Chemistry department. Use. Free testosterone is the fraction of total testosterone that is not bound to circulating proteins. The free fraction is available to diffuse into target cells to interact with receptors or enzymes. The concentration of free testosterone is low relative to total testosterone, typically <3% of the total testosterone concentration.The facility is located in room C1B90 of the Jennie Smoly Caruthers Biotechnology Building and currently houses five mass spectrometry systems that provide ...The automotive industry is constantly evolving, and one of the latest innovations that has captured the attention of car enthusiasts and eco-conscious drivers alike is the new EV6 SUV.It can be installed on a local server, or you can request a project on the PanoramaWeb.org server, hosted by the MacCoss Lab at the University of Washington. Access privileges within a project may be customized, allowing you to control fully who has access to data you publish to Panorama. [ Project Page] EncyclopeDIA is an open-source library ...

A mass spectrometer ionizes atoms and molecules with a high-energy electron beam and then deflects the ions through a magnetic field based on their mass-to-charge ratios ( m / z. ‍. ). The mass spectrum of a sample shows the relative abundances of the ions on the y-axis and their m / z. ‍. ratios on the x-axis. If z = 1.A Brief History of Mass Spectrometry. 1897 – Modern mass spectrometry (MS) is credited to the cathode-ray-tube experiments of J.J. Thomson of Manchester, England. 1953 – Wolfgang Paul’s invention of the quadrupole and quadrupole ion trap earned him the Nobel Prize in physics. 1968 – Malcolm Dole developed contemporary electrospray ... Table 1. Accurate Mass of Organic Solvents Table 2. Accurate Mass of Proton, Electron and Selected Elements Element Abbreviation Atomic Masses Electron e- 0.000549 Proton H+ 1.007276 Carbon-12 C-12 12.000000 Carbon-13 C-13 13.003355 Hydrogen H 1.007825 Deuterium D 2.014101 Oxygen O 15.994915 Oxygen-18 O-18 17.999160 Nitrogen-14 N …Liquid chromatography mass spectrometry (LC/MS) is performed on sample types that are thermally unstable, large, polar, ionic or non-volatile, or which need to be derivatized. Typical LC/MS samples include nucleotides, peptides, steroids, hormones, dyes, fatty acids, and alcohols. As a result, LC/MS is preferentially used in pharmacokinetics ...It can be installed on a local server, or you can request a project on the PanoramaWeb.org server, hosted by the MacCoss Lab at the University of Washington. Access privileges within a project may be customized, allowing you to control fully who has access to data you publish to Panorama. [ Project Page] EncyclopeDIA is an open-source library ...The School of Pharmacy Mass Spectrometry Facility was established in 2007 to centralize and organize the mass spectrometry instrumentation and proteomics capabilities. Since then, the facility has expanded again, with the arrival of the Reisdorph Lab in 2015. The facility now boasts over 13 mass spectrometers with capabilities spanning ...

The system is designed to minimize maintenance and possible delays in starting testing during clinical lab shifts. Maintenance checks can be scheduled off-hours so as not to interfere with laboratory throughput. Meanwhile, the daily start-up procedures take only 20 to 30 minutes and can be programmed to start just before working hours.Analytical Chemistry (Health and Environmental Applications Laboratory) Cell Media Facility; Electron Paramagnetic Resonance Lab; Glass Shop; High-Throughput Screening Facility; Laboratory Waste Collection; Mass Spectrometry Laboratory; Microanalysis Laboratory; Optically Stimulated Luminescence Dating Laboratory; Stable Isotope Laboratory ...Performance of a matrix-assisted laser desorption ionization-time-of-flight mass spectrometry system for the identification of bacterial isolates in the clinical routine laboratory. Clin Lab 2009 ; 55 : 289 – 96 . The automotive industry is constantly evolving, with new models and technologies being introduced year after year. One such exciting addition to the market is the 2023 Ioniq 6. The first thing that catches your eye when you see the 2023 Ion...MassBank of North America (MoNA) is a metadata-centric, auto-curating repository designed for efficient storage and querying of mass spectral records. It intends to serve as a the framework for a centralized, collaborative database of metabolite mass spectra, metadata and associated compounds. MoNA currently contains 0 mass spectral records ...

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Third floor renovations in the Conte Building (K) included the fit-out of a 20-year-old laboratory to accommodate the Mass Spectrometry Lab.Published June 18, 2021. Posted in: Analytical Chemistry and Chromatography Techniques. Mass spectrometry, also referred to as mass spec or MS, is an analytical technique that is becoming increasingly important in bioscience research. This article will introduce you to mass spectrometry in biological research, explain how it works, and how it ...Liquid chromatography coupled to Orbitrap Elite Mass spectrometry. High throughput Hybrid Ion Trap-Orbitrap Mass spectrometer capable of high mass accuracy and ...In the stick diagram showing the mass spectrum of pentane, the line produced by the heaviest ion passing through the machine (at m/z = 72) is due to the molecular ion. The tallest line in the stick diagram (in this case at m/z = 43) is called the base peak. This is usually given an arbitrary height of 100, and the height of everything else is ...

The Mann lab is a leader in the technology and application of mass spectrometry-based proteomics and has been at the forefront of the field for almost three decades. The core research interests of the group are signal transduction, biomarker discovery and metabolic diseases. Another focus is the development of mass spectrometric and proteomic ...Overseeing a mass spectrometry lab is a complex task, whether you're inheriting an already established lab or starting from the ground up. Through my journey of managing a mass spec lab, I learned invaluable lessons in change management—including strategies for implementing new instruments, leading staff, and of course, patience.Example: 1) Find Adduct: Taxol, C47H51NO14, M=853.33089. Enter 853.33089 in green box read M+22.9, m/z=876.320108. 2) Reverse: take 12 Tesla-FT-MS result out of MS m/z=876.330. suspect M+Na adduct, read M=853.340782, enter this value into formula finder with 2 ppm mass accuracy (CHNSOP enabled) get some thousand results, compare isotopic ... After 20 years in the mass spectrometry industry, we have been to many pharmacy companies, food manufacturers, product manufacturers, medical laboratories and environmental labs. We have solved problems, developed LDT methodologies, validated testing methods and designed labs. We have a passion for doing what seems impossible and sharing our ...Test Result Name. Result LOINC Value. Applies only to results expressed in units of measure originally reported by the performing laboratory. These values do not apply to results that are converted to other units of measure. 8859. T4 (Thyroxine), Free by Dialysis, S. 6892-4. Determining thyroid status of sick, hospitalized patients Determining ...Mass Spec Lab itself is a bio-analytical CRO, but as it grows it has carefully tried to distinguish itself as a Custom rather than Contract Research Organization. Let us explain. Mass Spec Lab formed in 2014 and launched its online presence in late 2015.Mass Spectrometry Lab School of Chemical Sciences University of Illinois Room 35 Noyes Lab, Box 51-1 600 S. Mathews Ave. Urbana, IL 61801-3602 We will check the samples in …Revolutionizing the clinical lab with mass spectrometry. Contributing lab leader : Robert de Jonge , Pieter Vermeersch , Michael Vogeser and Mads Nybo. While mass spectrometry (mass spec) is a common basic research tool, over the last decade, the technology has become more widely adopted for use in diagnostic testing in the clinical setting ...The Honda SL350 was a classic, vintage, dirt bike built from 1969 until 1973. It had lights, license plate bracket and instrumentation, making it street legal with many off-road features. The Honda SL350 was a classic, vintage, dirt bike bu...Contact Information Greg Barrett-Wilt, Ph.D. Director Room 2250 Biotechnology Center 425 Henry Mall Madison WI 53706 Email: [email protected] University of Wisconsin Biotechnology Center Mass Spectrometry Core Facility has several mass spectrometers for the analysis of biomolecules, including proteins, peptides, …The automotive industry is constantly evolving, with new models and technologies being introduced year after year. One such exciting addition to the market is the 2023 Ioniq 6. The first thing that catches your eye when you see the 2023 Ion...The Biological Mass Spectrometry Laboratory offers a wide range of services on a fee-for-service basis. Our outstanding experts will run your samples as well as ...

Inductively coupled plasma mass spectrometry. Inductively coupled plasma mass spectrometry ( ICP-MS) is a type of mass spectrometry that uses an inductively coupled plasma to ionize the sample. It atomizes the sample and creates atomic and small polyatomic ions, which are then detected. It is known and used for its ability to detect metals and ...

Mass Spectrometry, Liquid Chromatography, Informatics & Software Products. No matter whether you work in a routine testing lab or one for the discovery and development of life-changing drugs, you need the right tools, equipment and resources to achieve success. And when you trust Waters for your all your lab equipment needs, you’ll find a ...The laboratory team provides full support that includes consultation, project design, methodology development, and data analysis. Visit Mass Spectroscopy Lab Website University of Houston Department of Chemistry Lamar Fleming Jr. Building 3585 Cullen Blvd, Room 112 Houston, Texas 77204-5003 713-743-2701Lab Notebooks. Peer Review of Lab Notebooks; Technical Reports. Writing Guide; Figures; Title and Abstract; ... Mass Spec Practice; Structural ID Practice Problems ... of Loss of 43 (114 to 71) is likely C3H7, suggesting that fragment in the molecule. This also shows up as a peak at mass 43. There is little evidence for anything other than a ...In the future, mass spec could potentially be utilized in several diagnostic clinical labs, enabling better analytical quality and multiple steroid profiling with …Mass-spec Lab · Surface Imaging · AFM Lab · Clean Room. Mass Spec Lab. 1 - Inductively Coupled Plasma-Mass Spectrometry (ICP-MS) · 2 - Surface Plasmon Resonance ...Mass Spec Lab is an ideal partner for molecular structural elucidation using high resolution and high mass accuracy instrumentation. Our Ph.D. scientists have …OpenMS offers an open-source C++ library (+ Python bindings) for LC/MS data management, analysis and visualization. It empowers rapid development of mass spectrometry related software. OpenMS is freely available under the three clause BSD license and runs under Windows, macOS and Linux. The OpenMS members have a …Test Result Name. Result LOINC Value. Applies only to results expressed in units of measure originally reported by the performing laboratory. These values do not apply to results that are converted to other units of measure. 8859. T4 (Thyroxine), Free by Dialysis, S. 6892-4. Determining thyroid status of sick, hospitalized patients Determining ...The Agilent InfinityLab LC/MSD system uses the power of mass-selective detection to enhance analytical confidence. Designed for the chromatographer who wants to work more efficiently, the LC/MSD is the best solution for routine mass-selective detection. From basic pharmaceutical analysis to synthetic chemistry to routine food testing ...

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Our mass spectrometer is a high resolution instrument, capable of a resolution of 140,000@200 m/z FWHM with high accuracy (sub ppm mass accuracy). It can be ...Mass Spectrometry. We offer easy, high-throughput, quantitative workflows for proteins, drug metabolites, pesticides and many other applications. Whether you’re detecting disease biomarkers or performing forensic analysis on drugs of abuse, our mass spectrometers give you the resolution, accuracy, sensitivity, and throughput that you need to ...The Institute of Chemical Biology and Drug Discovery (ICB&DD) operates an Analytical Instrumentation Laboratory in the Chemistry department at SUNY-Stony Brook. This laboratory consists of three mass spectrometers at present. Two of these instruments are located in Lab 576 and are available to approved, qualified users on a 24/7 basis. The instrument used in this experiment is an Agilent 6890N GC/MS (low-resolution mass spectrometer) pictured in Figure 5.2. The mass spectrometer and GC are controlled by Chemstation software on the computer. This instrument can be found in room 3475. Figure 5.2: GC/MS Instrument used in this experiment. The Thermal Ionization Mass Spectrometry (TIMS) Laboratory is maintained by Professor Elizabeth Griffith. The laboratory, which is supplied with HEPA ...The Mass Spectrometry Center offers the following services: Instrument Training – Training services available to center users: Basic UPLC operation and gradient development. Compound optimization for quantitative assays. Basic mass spectrometry analysis on all center platforms. Software training for quantitative and qualitative analysis software. The Stable Isotope Mass Spectrometry Laboratory (SIMSL) in the Division of Biology at Kansas State University is managed by Wyatt Hansen and directed by Dr. Jesse Nippert. The SIMSL is dedicated to stable isotope and elemental analysis. SIMSL is equipped for the stable isotopic (‰) and elemental (%) composition analysis of carbon …These two factors are combined into the mass/charge ratio. Mass/charge ratio is given the symbol m/z (or sometimes m/e). For example, if an ion had a mass of 28 and a charge of 1+, its mass/charge ratio would be 28. An ion with a mass of 56 and a charge of 2+ would also have a mass/charge ratio of 28.Overseeing a mass spectrometry lab is a complex task, whether you're inheriting an already established lab or starting from the ground up. Through my journey of managing a mass spec lab, I learned invaluable lessons in change management—including strategies for implementing new instruments, leading staff, and of course, patience. ….

The “Manitoba II” is a central instrument in Mass Spec studies at U of M. It is a room-sized, high-resolution mass spectrometer that has set international standards for determining atomic masses. ... each connected to different machines in the lab. Part of TOF 3 Mass Spectrometer, built at the University of Manitoba, Physics Department c ...Mass Spectrometry · Application notes · Our equipment · Internal users · Take a look around our Mass Spectrometry lab · Enquiries · Use of Cookies on the University ...Exercise 4.1: Using the fragmentation patterns for acetone as a guide, predict the signals that you would find in the mass spectra of:. a) 2-butanone; b) 3-hexanone; c) cyclopentanone. Exercise 4.2: Predict some signals that you would expect to see in a mass spectrum of 2-chloropropane. Exercise 4.3: The mass spectrum of an aldehyde shows a …Performance of a matrix-assisted laser desorption ionization-time-of-flight mass spectrometry system for the identification of bacterial isolates in the clinical routine laboratory. Clin Lab 2009 ; 55 : 289 – 96 .LC-MS offers versatility and resolution. Liquid chromatography (LC) is a technique widely used to separate compounds from a sample prior to analysis and is frequently coupled to mass spectrometry. With LC, separation of the sample components is based on the interactions of the compounds with the mobile and stationary phases, and the degree of ...Testosterone, Total, S. 2986-8. Evaluating men with symptoms or signs of possible hypogonadism, such as loss of libido, erectile dysfunction, gynecomastia, osteoporosis, or infertility Evaluating boys with delayed or precocious puberty Monitoring testosterone replacement therapy Monitoring antiandrogen therapy (eg, used in prostate cancer ...Our mission is to bring state-of-the-art mass spectrometry expertise, methodology, and instrumentation to the University's research and clinical infrastructure. The Mass Spectrometry Laboratory (MSL) occupies about 2,000 square feet of space on the first floor of Kolthoff Hall as part of the LeClaire-Dow Instrumentation Facility, and is located ... Mass Spectrometry Lab Introduction. Mass spectrometry (MS) is an analytical technique that measures the mass-to-charge ratio of charged particles. It is used for determining masses of particles, for determining the elemental composition of a sample or molecule. The MS principle consists of ionizing chemical compounds to generate charged ... However, before these breakthroughs can take place, there is a need for better mass spec automation, cost-effectiveness, implementation, and training of lab personnel. 3 By addressing these challenges, lab leaders are more likely to widely adopt mass spec-based proteomics to fulfill unmet clinical needs in current clinical care pathways.Learning Hub Success Programs offer a comprehensive training option, with personalized, blended online and in-person courses. Successful completion provides you with a workflow certificate. Each program is purposefully designed based on renowned spaced learning models that are proven to maximize your knowledge retention by up to 16-times. Mass spec lab, Mass Spectrometry Laboratory Since 1965, the Mass Spectrometry Facility (MSF) has provided top-quality mass spectrometry support to the faculty research groups of the Indiana University-Bloomington. The MSF is one of many technical support facilities in the Chemistry department. , Mass spectrometry (MS) is a valuable tool that can give you vast amounts of MS data to help you identify and quantify components. MS has been used to discover, determine, and quantify sample compounds in the proteomics, metabolomics, imaging, and glycomics applications across the food, pharmaceutical, and environmental industries. Combining …, Mass spectrometry (MS) is a valuable tool that can give you vast amounts of MS data to help you identify and quantify components. MS has been used to discover, determine, and quantify sample compounds in the proteomics, metabolomics, imaging, and glycomics applications across the food, pharmaceutical, and environmental industries. Combining MS with appropriate software and computer technology ..., Overseeing a mass spectrometry lab is a complex task, whether you're inheriting an already established lab or starting from the ground up. Through my journey of managing a mass spec lab, I learned invaluable lessons in change management—including strategies for implementing new instruments, leading staff, and of course, patience. , LC-MS offers versatility and resolution. Liquid chromatography (LC) is a technique widely used to separate compounds from a sample prior to analysis and is frequently coupled to mass spectrometry. With LC, separation of the sample components is based on the interactions of the compounds with the mobile and stationary phases, and the degree of ..., Basics of FT-IR Spectroscopy Molecular Spectroscopy. Liquid chromatography mass spectrometry (LC-MS) is an indispensable tool for quantitative and qualitative analysis in a wide range of fields, from pharmaceuticals and food science to environmental analysis. This site provides basic knowledge of LC-MS., Mass spectrometry. Mass spectrometry ( MS) is an analytical technique that is used to measure the mass-to-charge ratio of ions. The results are presented as a mass spectrum, a plot of intensity as a function of the …, The X500 QTOF series are the first accurate mass systems that can deliver true qualitative and quantitative results in a single injection, and coupled with SWATH acquisition software, can lift your lab to new heights whether you’re performing routine testing or more advanced analyses. Our Triple Quad mass spectrometers revolutionize ..., The system is designed to minimize maintenance and possible delays in starting testing during clinical lab shifts. Maintenance checks can be scheduled off-hours so as not to interfere with laboratory throughput. Meanwhile, the daily start-up procedures take only 20 to 30 minutes and can be programmed to start just before working hours. , Discover a wide range of Bruker LabScape Services and Support to ensure maximum operational efficiency of your instruments. We’ve got you covered! To the LabScape Solutions. High quality consumables, accessories and software, essential for the day to day operation of your Magnetic Resonance, Mass Spectrometry, Diffractometer & Scattering ..., This system offers productivity, reliability, and robustness in a modernized entry-level mass spec for today’s analytical laboratories. The Triple Quad 3500 system offers the speed and precision you want from a modern mass spec system, with the legendary performance and dependability you trust from SCIEX technology., Mass spectrometry potentially enables new screening and clinically relevant tests and supports developing targeted therapeutics. Bridging the gap from discovery to verification and validation requires high-performing instruments and software, as well as high-level competence in MS-based biomarker discovery and in method development for ... , Announcement: The Garcia Lab has moved to the Washington University School of Medicine in St. Louis (July 2021). Ben is now the Head of the Dept of Biochemistry and Molecular Biophysics and will also help guide the development of a new Mass Spectrometry Center! Press release can be read here. Welcome to the Garcia Lab “Spectrometry for the ..., Mass Spectrometry Lab Introduction. Mass spectrometry (MS) is an analytical technique that measures the mass-to-charge ratio of charged particles. It is used for determining masses of particles, for determining the elemental composition of a sample or molecule. The MS principle consists of ionizing chemical compounds to generate charged ... , Mass Spec Lab is a specialty analytical laboratory business created to serve industries requiring custom state-of-the-art chemical analysis of substances and samples, including pharmaceuticals, biomedical , biotechnology and related businesses., In today’s digital age, having a reliable and efficient device is crucial for both work and personal use. When it comes to portable computing options, two popular choices are Chromebooks and laptops., Mass spectrometry is a technique that identifies analytes based on mass-to-charge (m / z) ratio and structural fragments. Although this technique has been used in research and specialized clinical laboratories for decades, only in recent years has mass spectrometry become popular in routine clinical laboratories., Anne Marie Helmenstine, Ph.D. Updated on February 01, 2019. Mass spectrometry (MS) is an analytical laboratory technique to separate the components of a sample by their mass and electrical charge. The instrument used in MS is called mass spectrometer. It produces a mass spectrum that plots the mass-to-charge (m/z) ratio of compounds in a mixture., Users from outside the University of Illinois need to fill out a Technical Testing Agreement before sending samples. Samples should be mailed to: Attention: Furong Sun. Mass Spectrometry Lab. School of Chemical Sciences. University of Illinois. Room 35 Noyes Lab, Box 51-1. 600 S. Mathews Ave. Urbana, IL 61801-3602., 15 Jul 2021 ... ... Lab went live with reporting plasma catecholamines by liquid chromatography tandem mass spectrometry. No other clinical diagnostic lab in ..., Basics of FT-IR Spectroscopy Molecular Spectroscopy. Liquid chromatography mass spectrometry (LC-MS) is an indispensable tool for quantitative and qualitative analysis in a wide range of fields, from pharmaceuticals and food science to environmental analysis. This site provides basic knowledge of LC-MS., The Mass Spectrometry Laboratory at Everson Hall of UC Davis is the home of analytical core laboratories for: ​. UC Davis Superfund Research Program., The CCE Multiuser Mass Spectrometry lab in Crellin B170 is a shared mass spectrometry laboratory. The mass spectrometers in this lab have been using funds from NSF (CRIF and MRSEC programs), Hughes Foundation, DOW, and CCE Division funds. , Commercial software for XIC of peptide level mass spec data from any mass spec vendor and relative quan of PTM vs unmodified. Specialized for biopharmaceutical applications. ... (Apache 2.0) Windows client software developed in the MacCoss lab at University of Washington that supports building Selected Reaction Monitoring (SRM) / Multiple ..., W elcome to the web home of the Vincent Coates Foundation Mass Spectrometry Laboratory, a University-wide VPDoR resource. The laboratory is named in honor of a generous gift from Vi ncent and Stella Coates to support the mass spec & proteomics facility as a shared core resource. It is a BioX core, embodying the Bio-X spirit of interdisciplinary ..., Revolutionizing the clinical lab with mass spectrometry. Contributing lab leader : Robert de Jonge , Pieter Vermeersch , Michael Vogeser and Mads Nybo. While mass spectrometry (mass spec) is a common basic research tool, over the last decade, the technology has become more widely adopted for use in diagnostic testing in the clinical setting ..., Hyundai has been making waves in the electric vehicle (EV) market with its latest offering – the Hyundai Ioniq 5. This all-electric SUV boasts impressive features and specs that make it a serious contender among EVs., Our mission is to bring state-of-the-art mass spectrometry expertise, methodology, and instrumentation to the University's research and clinical infrastructure. The Mass Spectrometry Laboratory (MSL) occupies about 2,000 square feet of space on the first floor of Kolthoff Hall as part of the LeClaire-Dow Instrumentation Facility, and is located ... , The School of Pharmacy Mass Spectrometry Facility was established in 2007 to centralize and organize the mass spectrometry instrumentation and proteomics capabilities. Since then, the facility has expanded again, with the arrival of the Reisdorph Lab in 2015. The facility now boasts over 13 mass spectrometers with capabilities spanning ... , Feb 1, 2019 · Anne Marie Helmenstine, Ph.D. Updated on February 01, 2019. Mass spectrometry (MS) is an analytical laboratory technique to separate the components of a sample by their mass and electrical charge. The instrument used in MS is called mass spectrometer. It produces a mass spectrum that plots the mass-to-charge (m/z) ratio of compounds in a mixture. , The Mass Spectrometry Laboratory at Chemical Department Rutgers-Newark is located in the Life Science Center, room 001, at 225 University Avenue, and Olson Hall, room 006, at 73 Warren Street, Newark, NJ. Please contact us at: Phone: 973-353-5254; e-mail: [email protected] , Contact us today for your Gas Chromatography Mass Spectrometry (GC-MS) needs at +1 800-366-3867 or please complete the form below to have an EAG expert contact you. *Currently our 800 phone number is not working correctly. Please use +1 314-291-6620 or complete the form below*. First Name*. Last Name*., Teaching Mass Spec for Chemists; ... With the daily need to analyze a variety of samples, these techniques are indispensable in a busy lab. Learn how a single instrument can be adapted to each of these sample requirements and rapidly changed to accommodate back-to-back assays. Listen to users in the field speak about the …