Richard weinshilboum

The man who led the mapping of the genome for the NIH has no doubt about Dr. Weinshilboum's leadership in the PGRN and in the science. Francis Collins, M.D., now heads the National Institutes of Health. "Dick is one of the foremost pioneers in the field of pharmacogenomic research," says Francis Collins, M.D., Ph.D., now director of the NIH.

Antidepressants have reduced the symptom burden for many Major Depressive Disorder (MDD) patients, but drug-related side effects and treatment resistance continue to present major challenges. Pharmacogenomics represents one approach to enhance antidepressant efficacy and avoid adverse reactions, but concerns remain with regard to the overall ...Richard Weinshilboum, MD Professor of Pharmacology and Medicine and Dasburg Professor of Cancer Genomics Research Mayo Clinic. LISTEN ON-DEMAND. Recorded August 17, 2021 | Episode 1 Supporting Precision Oncology with Precision Pathology: The Promise and Challenges of a New Paradigm in Medicine.Jan 11, 2021 · Psychiatry and psychopharmacology participated actively in the early development of pharmacogenetics with reports decades ago of genetic variation in human genes encoding proteins of importance for psychiatry such as the catecholamine metabolizing enzyme catechol O-methyltranferase (COMT) (Weinshilboum and Raymond, 1977; Scanlon et al., 1979 ... An Evidence-Based Framework for Evaluating Pharmacogenomics Knowledge for Personalized Medicine. Clinical pharmacology and therapeutics. 2021. Whirl-Carrillo Michelle, Huddart Rachel, Gong Li, Sangkuhl Katrin, Thorn Caroline F, Whaley Ryan and Klein Teri E. PMID: 34216021 DOI: 10.1002/cpt.2350. Please consult the citation policy on how to cite ...Apr 1, 2001 · Send reprint requests to: Richard Weinshilboum, M.D., Department of Pharmacology, Mayo Medical School/Mayo Graduate School/Mayo Clinic, Rochester, MN 55905. E-mail: weinshilboum.richard{at}mayo.edu. Supported in part by National Institutes of Health RO1 Grants GM 28157 and GM 35720. Abbreviations used are:: TPMT thiopurine methyltransferase RBC On Jan. 31 in Rochester, Minn., Dr. Richard Weinshilboum talks about the significance of the mini-brain research that Mayo Clinic is performing. Ken Klotzbach for MPR News A unique partnership

Pharmacogenetics is the study of inherited variation in drug response. Genetic differences in drug metabolism are the most common causes for inherited variations in drug response or adverse reactions to medications. Methyl conjugation is an important pathway in the biotransformation of many drugs. Experiments performed during the past decade ... Richard Weinshilboum, M.D. *AskMayoExpert is an online tool available to Mayo Clinic and Mayo Clinic Care Network physicians. Join our community. Get the latest news from the Center for Individualized Medicine. Visit our blog, Facebook, LinkedIn or Twitter at @MayoClinicCIM.Richard Weinshilboum, MD, is the Mary Lou and John H Dasburg Professor for Cancer Genomics Research, Chair of the Division of Clinical Pharmacology and a Professor of Molecular Pharmacology and ...Other researchers on the study were Apua Paquola, Callie Fredlender, Kelly Heard, Yalin Deng, Amy Le, Sonia Dave, Lianna Fung, Xinyi Li and Maria Marchetto of the Salk Institute; and Yuan Ji, Michelle Skime, Timothy Nelson, Daniel Hall-Flavin and Richard Weinshilboum of the Mayo Clinic.Introduction. Primary prevention of breast cancer remains a major goal for reducing the burden associated with this disease. Two large breast cancer prevention trials of selective estrogen receptor modulators (SERMs) including the National Surgical Adjuvant Breast and Bowel Project (NSABP) P-1 placebo-controlled trial of tamoxifen [] and double-blind NSABP P-2 trial comparing raloxifene to ... Drew R Neavin 1 , Duan Liu 2 , Balmiki Ray 3 , Richard M Weinshilboum 4 Affiliations 1 Mayo Clinic Graduate School of Biomedical Sciences, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN 55902, USA. [email protected]. 2 Division of Clinical Pharmacology, Department of Molecular Pharmacology and ...

While some would like to drape the mantle "The father of pharmacogenomics" on Richard Weinshilboum, M.D., the scientist parries: "The only thing that I'm father of is my two children.". Either way, no one can argue that this charming, self-deprecating, diminutive gentleman is a titan in his field; and a giant reason Mayo can claim three decades of leadership in propelling this exploding ...Metabolomics is the study of metabolism at the global level. This rapidly developing new discipline has important potential implications for pharmacologic science. The concept that metabolic state is representative of the overall physiologic status of the organism lies at the heart of metabolomics. Metabolomic studies capture global biochemical ...Richard Weinshilboum and Liewei Wang are cofounders of and stockholders in OneOme LLC, a pharmacogenomic decision support company. John L. Black and the Mayo Clinic have licensed intellectual property to AssureX Health (Myriad) and received royalties. He is also a co-founder of OneOme LLC and, with Mayo Clinic, has intellectual …Send reprint requests to: Dr. Richard Weinshilboum, Dept. of Molecular Pharmacology and Experimental Therapeutics, Mayo Medical School-Mayo Clinic-Mayo Foundation, Rochester, MN 55905-0001. E-mail: weinshilboum.richard{at}mayo.edu.

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Oct 26, 2022 · Richard Weinshilboum, MD, who is co-director of the Pharmacogenomics Program at Mayo Clinic's Center for Individualized Medicine and chair of the Division of Clinical Pharmacology, and his team ... Credit: Arjun Athreya, Liewei Wang and Richard Weinshilboum; Dept of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic IUCRC: Industry-University Cooperative Research Centers Program. The National Science Foundation 2415 Eisenhower Ave. Alexandria, VA 22314. USA Tel: (703) 292-5111He succeeds Richard Weinshilboum, M.D., who provided outstanding leadership as the interim director of the Center for Individualized Medicine following the departure of Keith Stewart, M.B., Ch.B., in 2020. Dr. Weinshilboum played a critical role in advancing the center's 10-year strategic plan in alignment with Mayo Clinic's 2030 strategy, and ...Richard M Weinshilboum MD. Clinical Pharmacology Unit, Department of Pharmacology, Mayo Foundation/Mayo Clinic. Richard Weinshilboum MD, Department of Pharmacology, Mayo Clinic/Mayo Foundation, Rochester, MN 55905.Search for more papers by this author. Mary C Scott PhD,Ming-Fen Ho 1 , Cheng Zhang 2 , Irene Moon 2 , Lixuan Wei 2 , Brandon Coombes 3 , Joanna Biernacka 3 , Michelle Skime 4 , Doo-Sup Choi 2 , Mark Frye 4 , Kristen Schmidt 5 , Kate Gliske 5 , Jacqueline Braughton 5 , Quyen Ngo 5 , Cedric Skillon 5 , Marvin Seppala 5 , Tyler Oesterle 4 , Victor Karpyak 4 , Hu Li 2 , Richard Weinshilboum 6

Ye Zhu # 1 2 , Kristi M Swanson # 1 , Ricardo L Rojas 3 , Zhen Wang 1 4 , Jennifer L St Sauver 1 5 , Sue L Visscher 1 , Larry J Prokop 6 , Suzette J Bielinski 5 , Liewei Wang 7 , Richard Weinshilboum 7 , Bijan J Borah 8 9Caption: Richard Weinshilboum, MD, studies pharmacogenomics—the role of inheritance and individual variation in DNA sequence or structure in drug response. The goal is to develop safer and more effective drug therapy to treat diseases ranging from cancer to depression. Coimmunoprecipitation identified a series of ERICH3 interacting proteins including clathrin heavy chain which are known to play a role in vesicular function. Immunofluorescence showed ERICH3 colocalization with 5-HT in vesicle-like structures, and ERICH3 knock-out dramatically decreased 5-HT staining in SK-N-SH cells as well as 5-HT ...Drew R. Neavin, 1 Duan Liu, 2 Balmiki Ray, 2, † and Richard M. Weinshilboum 2, * Drew R. Neavin 1 Mayo Clinic Graduate School of Biomedical Sciences, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, MN 55902, USA; [email protected]. It is estimated that over 2.2 million breast cancer cases occurred worldwide in 2020, representing 1 in 4 cancers diagnosed among women [1, 2].The molecular classification of breast cancer is based on human epidermal growth factor receptor-2 (HER2) gene amplification and the expression of sex hormones, estrogen, and progesterone receptors.Richard Weinshilboum, M.D., interim director for the Center for Individualized Medicine, is helping to lead Mayo's efforts to integrate pharmacogenomics into clinical practice. He says Dr. Cutrer's study is just one example of how the center is working to improve treatments and reduce harmful side effects.Focus Areas. Dr. Weinshilboum's research program is focused on pharmacogenomics, the study of the role of inheritance in variation among patients in drug response phenotypes — phenotypes that can vary from severe life-threatening adverse drug reactions at one end of the spectrum to lack of the desired therapeutic drug effect at the other.

Pharmacogenetics is the study of inherited variations in drug response Pharmacogenetics uses the techniques of pharmacology, population genetics, biochemical genetics and, most recently, molecular bi...

Richard Weinshilboum MD, Clinical Pharmacology Unit, Department of Pharmacology, Mayo Clinic/Mayo Foundation, Rochester, MN 55905. Search for more papers by this author First published: November 1989Dr. Richard Weinshilboum, whom some have called the father of pharmacogenomics, has been a pioneer in this field of research for three decades. He’s also an internist, professor of medicine and ...Oct 26, 2022 · Richard Weinshilboum, MD, who is co-director of the Pharmacogenomics Program at Mayo Clinic's Center for Individualized Medicine and chair of the Division of Clinical Pharmacology, and his team ... Richard Weinshilboum; Anastrozole is a widely prescribed aromatase inhibitor for the therapy of estrogen receptor positive (ER+) breast cancer. We performed a genome‐wide association study (GWAS ...Richard Weinshilboum, M.D. From the Departments of Molecular Phar-macology and Experimental Therapeutics and Medicine, Mayo Medical School, Mayo Clinic, and Mayo Foundation, Rochester,An Evidence-Based Framework for Evaluating Pharmacogenomics Knowledge for Personalized Medicine. Clinical pharmacology and therapeutics. 2021. Whirl-Carrillo Michelle, Huddart Rachel, Gong Li, Sangkuhl Katrin, Thorn Caroline F, Whaley Ryan and Klein Teri E. PMID: 34216021 DOI: 10.1002/cpt.2350. Please consult the citation policy on how to cite ...The CUSBEA (China-United States Biochemistry Examination and Application) program was implemented during the 8 years between 1982 and 1989, with a total of 422 Ph.D. students selected and placed in over more than 90 top universities in the United States (1-3).The original aim of this program was to train bright young Ph.D. scientists in the field of Biochemistry and molecular biology, with ...Here we report a novel role of nuclear PD-L1 in regulation of the cohesin complex. Our findings show that PD-L1, compensating for the loss of Sororin, competes with WAPL binding to PDS5B and ...Richard Weinshilboum, M.D., is chair of the Division of Clinical Pharmacology and a professor of medicine and pharmacology at Mayo Clinic College of Medicine and Science. Contact Get in touch with the Department of Molecular Pharmacology and Experimental Therapeutics about ongoing research projects and opportunities for collaboration or training.

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AU - Weinshilboum, Richard. AU - Borah, Bijan J. N1 - Funding Information: The value of pharmacogenomics has not been unequivocally established, particularly surrounding pre-emptive and panel testing approaches. Standardized modeling approaches and high-quality reporting are needed.Dive into the research topics where Richard M Weinshilboum is active. These topic labels come from the works of this person. Together they form a unique fingerprint.Dr. Weinshilboum has devoted decades to researching the mechanisms responsible for large individual variation in drug toxicity or efficacy for diseases as diverse as depression, childhood leukemia and breast cancer. His remarks were made at Mayo Medical School during the second annual Mrazek Lecture, titled "SSRI Pharmacogenomics."Richard Weinshilboum; Anastrozole is a widely prescribed aromatase inhibitor for the therapy of estrogen receptor positive (ER+) breast cancer. We performed a genome‐wide association study (GWAS ... The 3β-hydroxysteroid dehydrogenase/Δ 5-Δ 4 isomerase isoenzymes 1 and 2 (HSD3B1 and HSD3B2) are membrane-bound enzymes that play essential roles in the biosynthesis of steroid hormones. Therefore, variation in the HSD3B1 and HSD3B2 genes might play a role in the pathophysiology of steroid hormone-related disease. We set out to systematically identify common polymorphisms and haplotypes in ...Correction to: Establishing and characterizing patient-derived xenografts using pre-chemotherapy percutaneous biopsy and post-chemotherapy surgical samples from a prospective neoadjuvant breast cancer studyU.S. Citizens with emergencies, please call +91-11-2419-8000. Outside of Office Hours, contact: +91-11-2419-8000. Outside of India: 011-91-11-2419-8000Rochester, Minnesota Driving directions More info Billing & insurance Accessibility services Education 1972 Senior Resident - Internal Medicine Massachusetts General Hospital 1971 Fellow PRAT, NIMH, National Institutes of Health Show more education Activities and honors Certifications 1991Aksoy S, Szumlanski CL, Weinshilboum RM.. Human liver nicotinamide N-methyltransferase. cDNA cloning, expression, and biochemical characterization. J Biol Chem 269: 14835-14840Conclusion. We found mixed evidence on the cost-effectiveness of PGx in CVD care. Supportive evidence exists for clopidogrel-CYP2C19 and warfarin-CYP2C9/VKORC1, but evidence is limited in other drug-gene combinations.Gaps persist, including unclear explanation of perspective and cost inputs, underreporting of study design elements critical to economic evaluations, and limited examination ... ….

Richard WEINSHILBOUM, Da burg Professor of Cancer Genomics Research, Professor of Pharmacology and Medicine | Cited by 45,330 | of Mayo Foundation for Medical …"As Dr. Richard Weinshilboum, one of my mentors, says: 'It's about the right drug, at the right dose, for the right patient.' That's what we need to focus on." Learn more. Watch Dr. Matthew Goetz discuss systemic therapies for breast cancer in this "Mayo Clinic Q&A" podcast video:Available until October 31, 2025 - Online CME Course Pharmacogenomics (PGx) is the study of how one’s genes may affect an individual's response to medication and is an emerging field within patient care. Mayo Clinic experts have created an online certificate program on how to integrate PGx into clinical practice for pharmacists, physicians, nurse …In this issue, Yonker et al. report that multisystem inflammatory syndrome in children (MIS-C) is associated with increased gastrointestinal mucosal permeability. They suggest this could allow SARS-CoV-2 antigens in the gastrointestinal tract to leak into the bloodstream, triggering cytokine storm and hyperinflammatory responses.Dr. Richard M. Weinshilboum is a Internist in Rochester, MN. Find Dr. Weinshilboum's phone number, address, hospital affiliations and more.Research conducted under Dr. Richard Weinshilboum., Mayo Clinic Graduate School, Rochester, WI 2007 to 2007: Human Genome Analysis: Genetic Analysis of Multifactorial Disease, Wellcome Trust Institute 1996 to 2000: BS, Biochemistry and Molecular Biology, University of Wisconsin Eau Claire, Eau Claire, WI.Send reprint requests to: Dr. Richard Weinshilboum, Dept. of Molecular Pharmacology and Experimental Therapeutics, Mayo Medical School-Mayo Clinic-Mayo Foundation, Rochester, MN 55905-0001. E-mail: weinshilboum.richard{at}mayo.edu.AU - Weinshilboum, Richard. AU - Borah, Bijan J. N1 - Funding Information: The value of pharmacogenomics has not been unequivocally established, particularly surrounding pre-emptive and panel testing approaches. Standardized modeling approaches and high-quality reporting are needed.Introduction. Glutathione S-transferase P1 (GSTP1) is a member of the cytosolic GST superfamily (1-3).These "phase II" enzymes catalyze the glutathione conjugation of a variety of electrophilic xenobiotics, including substrates that range from environmental toxins and carcinogens to drugs used in the treatment of cancer (3-6).Variation in the expression and activity of GSTP1 has been ...Dr. Weinshilboum says this study is a steppingstone in developing the foundations necessary to use DNA sequencing in helping to guide clinical care. Key components in the successful implementation of this study included pharmacogenomics education programs for medical staff, information technology support to build and implement the data ... Richard weinshilboum, Richard Weinshilboum Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Mayo Clinic College of Medicine, Rochester, MN. Corresponding author: Richard Weinshilboum, [email protected]. Search for other works by this author on: ..., Sep 9, 2019 · Richard Weinshilboum. Division of Clinical Pharmacology, Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota, USA. Search for more papers by this author , Richard Weinshilboum. 2015, Clinical pharmacology and therapeutics. The scaling up of data in clinical pharmacology and the merger of systems biology and pharmacology has led to the emergence of a new discipline of Quantitative and Systems Pharmacology (QSP). This new research direction might significantly advance the discovery, development and ..., Aug 31, 2021 · Dr. Lazaridis succeeds Richard Weinshilboum, M.D., who has provided outstanding leadership as the interim director of the Center for Individualized Medicine following the departure of Keith Stewart, M.B., Ch.B., in 2020. Dr. , Richard Weinshilboum is a Professor of Medicine and Pharmacology. His research focuses on pharmacogenetics and pharmacogenomics, and his studies have resulted in the discovery and characterization of a series of functionally and clinically important genetic polymorphisms and the rapid “translation” of that information into clinical studies ..., Joanna M. Biernacka, 1, 2 Brandon J. Coombes, 1 Anthony Batzler, 1 Ada Man-Choi Ho, 2 Jennifer R. Geske, 1 Josef Frank, 3 Colin Hodgkinson, 4 Michelle Skime, 2 Colin Colby, 1 Lea Zillich, 3 Sofia Pozsonyiova, 1 Ming-Fen Ho, 5 Falk Kiefer, 6 Marcella Rietschel, 3 Richard Weinshilboum, 5 Stephanie S. O'Malley, 7 Karl Mann, 6 Ray Anton, 8 David ..., Richard Weinshilboum, M.D., professor of pharmacology and medicine and Dasburg Professor of Cancer Genomics Research at Mayo Clinic, said, “I’ve been at Mayo Clinic for a long time, and this alliance—institution to institution—has been the most positive and most productive I’ve seen.” With the explosion of big data in medicine ..., [email protected]. # Contributed equally. PMID: 34535768 PMCID: PMC8872993 DOI: 10.1038/s41380-021-01274-z Abstract Bipolar disorder (BD) and obesity are highly comorbid. We previously performed a genome-wide association study (GWAS) for BD risk accounting for the effect of body mass index (BMI), …, Dr. Richard Weinshilboum, MD is an internal medicine specialist in Rochester, MN and has over 50 years of experience in the medical field. He graduated from University of Kansas School of Medicine in 1972. 0 (0 ratings) Leave a review. Practice. 200 1st St SW Rochester, MN 55905., and Richard M. Weinshilboum, M.D. From the Di vision of Clin ical Pharm acol-ogy, Departmen t of Mol ecular Pharma-cology and E xperime ntal Thera peutics, Mayo Medical School, Mayo Clinic, Roch-, Richard M. Weinshilboum, MD Rochester, Minn. Xanthine oxidase (EC 1.2.3.2) is a cytoplasmic en- zyme that catalyzes the oxidation of endogenous pu-, Antiestrogen pathway shows the rate-limiting biosynthesis of estrogen from androgens by aromatase and its inhibition by aromatase inhibitors/inactivators in postmenopausal women ( Fig. 1 ). Aromatase, an enzyme of the cytochrome P450 subfamily and the product of the CYP19A1 gene, is highly expressed in the placenta and in the granulose cells of ..., Richard Weinshilboum, M.D. Dr. Weinshilboum studies pharmacogenomics — the role of inheritance and individual variation in DNA sequence or structure in drug response. The goal is to develop safer and more effective drug therapy to treat diseases that range from cancer to depression., D M Otterness's 46 research works with 3,394 citations and 1,641 reads, including: Human 3′-Phosphoadenosine 5′-Phosphosulfate Synthetase 1 (PAPSS1) and PAPSS2: Gene Cloning, Characterization ..., Dr. Richard Weinshilboum, with over 40 years of research and clinical experience, sets the stage for this pharmacogenomics (PGx) course. He presents key, foundational principles, examples of early and current research, testing options and the trajectory of PGx in practice. Pharmacogenomics Primer, In this issue, Yonker et al. report that multisystem inflammatory syndrome in children (MIS-C) is associated with increased gastrointestinal mucosal permeability. They suggest this could allow SARS-CoV-2 antigens in the gastrointestinal tract to leak into the bloodstream, triggering cytokine storm and hyperinflammatory responses., Richard Weinshilboum is a Professor of Medicine and Pharmacology. His research focuses on pharmacogenetics and pharmacogenomics, and his studies have resulted in the discovery and characterization of a series of functionally and clinically important genetic polymorphisms and the rapid “translation” of that information into clinical studies ..., Funding support for the Pharmacogenomics Research Network Antidepressant Medication Pharmacogenomic Study (PGRN-AMPS) was provided by the National Institute of General Medical Sciences (NIGMS), National Institutes of Health (NIH), through the PGRN grant to Principal Investigators R. Weinshilboum and L. Wang (U19 …, These abnormal features could lead to too much neuronal communication in some areas of the brain and not enough in other parts, altering communication within the serotonergic circuitry and explaining why SSRIs do not always work to treat MDD. "These results contribute to a new way of examining, understanding, and addressing depression ..., Richard Weinshilboum, M.D. *AskMayoExpert is an online tool available to Mayo Clinic and Mayo Clinic Care Network physicians. Join our community. Get the latest news from the Center for Individualized Medicine. Visit our blog, Facebook, LinkedIn or Twitter at @MayoClinicCIM., Antiestrogen pathway shows the rate-limiting biosynthesis of estrogen from androgens by aromatase and its inhibition by aromatase inhibitors/inactivators in postmenopausal women ( Fig. 1 ). Aromatase, an enzyme of the cytochrome P450 subfamily and the product of the CYP19A1 gene, is highly expressed in the placenta and in the granulose cells of ..., Richard Weinshilboum is a Professor of Medicine and Pharmacology. His research focuses on pharmacogenetics and pharmacogenomics, and his studies have resulted in the discovery and characterization of a series of functionally and clinically important genetic polymorphisms and the rapid “translation” of that information into clinical studies ..., Richard Weinshilboum; Molecular Psychiatry (2021) A metabolome-wide association study in the general population reveals decreased levels of serum laurylcarnitine in people with depression ..., Ming-Fen Ho & Richard Weinshilboum. Department of Addictive Behavior and Addiction Medicine, Central Institute of Mental Health, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany ..., According to Richard Weinshilboum, M.D., a professor of pharmacology at the Mayo Clinic, there are a couple of factors that may explain the disappointing returns. “Phenotypic heterogeneity [in depression] is a major problem” when trying to identify biomarkers for depression, he told Psychiatric News., Richard Weinshilboum;. Richard Weinshilboum. 3Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota. Search ..., Dr Weinshilboum is a cofounder of and stockholder in OneOme LLC, a pharmacogenomics decision-support company. Dr Choi is a scientific advisory board member for Peptron Inc. Dr Frye reports grant support from Assurex Health, Mayo Foundation, Medibio Consultant (Mayo)—Actify Neurotherapies, Allergan, Intra-Cellular Therapies Inc., Janssen ..., Richard Weinshilboum. View author publications. You can also search for this author in PubMed Google Scholar ..., Aksoy S, Szumlanski CL, Weinshilboum RM.. Human liver nicotinamide N-methyltransferase. cDNA cloning, expression, and biochemical characterization. J Biol Chem 269: 14835-14840, The man who led the mapping of the genome for the NIH has no doubt about Dr. Weinshilboum's leadership in the PGRN and in the science. Francis Collins, M.D., now heads the National Institutes of Health. "Dick is one of the foremost pioneers in the field of pharmacogenomic research," says Francis Collins, M.D., Ph.D., now director of the NIH., Article. The involvement of estrogens in carcinogenic processes within the breast has been appreciated for a number of years (1–3). The classical concept of estrogens as carcinogens recognizes the mitogenicity of estrogens via estrogen receptor (ER)-mediated cellular events (1). More recently, as has been detailed throughout this …, Dr. Richard Merle Weinshilboum, MD, is a specialist in internal medicine who treats patients in Rochester, MN. This provider has 56 years of experience and is affiliated with Fairview Lakes Medical Center., Lily Weinshilboum, 86, a 51-year resident of Rochester, passed away peacefully in her home, surrounded by the family she cherished, after battling a catastrophic vascular diagnosis earlier this year.